Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents

Detalhes bibliográficos
Autor(a) principal: Araújo, Lucele Gonçalves Lima
Data de Publicação: 2022
Outros Autores: Rodrigues, Vandilson Pinheiro, Silva, Melaine Mont’Alverne Lawall, Azevedo, Gabrielle Cristinne Alves, Monteiro, Pablo de Matos, Ferreira, João Marcelo Saraiva, Sousa, Huderson Macedo de
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/2356
Resumo: Introduction: Hematological cancers are important causes of death in childhood and adolescence. Objective: To design the demographic and clinical profile of cases of hematological cancer reported for children and adolescents in a referral hospital in the city of São Luís, Maranhão, Brazil. Method: A retrospective observational study with secondary data collected from medical records of bone marrow tumor cases in patients aged up to 19 years registered in a public referral hospital for cancer treatment from 2005 to 2015. Patient’s profile was collected in addition to follow-up data. The chi-square and Fisher’s exact test were used in the statistical analysis. The significance level was 5% (p<0.05). Results: Cases of death were higher in patients diagnosed with non-Hodgkin’s lymphoma. Most patients with lymphoid leukemia were males aged up to 5 years, and the frequency of death in patients with lymphoid leukemia was lower in confirmed cases of type B lymphoblastic precursor cell leukemia when compared to the other categories. Conclusion: The findings suggest that most patients aged up to 19 years diagnosed with lymphoid leukemia were males and aged up to 5 years old.
id INCA-1_0d05335ac80b9ee996190d6f6db0cdae
oai_identifier_str oai:rbc.inca.gov.br:article/2356
network_acronym_str INCA-1
network_name_str Revista Brasileira de Cancerologia (Online)
repository_id_str
spelling Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and AdolescentsPerfil Demográfico y Clínico de Casos de Neoplasias Hematológicas en Niños y AdolescentesPerfil Demográfico e Clínico de Casos de Neoplasias Hematológicas em Crianças e Adolescentesneoplasias hematológicasdemografiamortalidadecriançaadolescentehematologic neoplasmsdemographymortalitychildadolescentneoplasias hematológicasdemografíamortalidadniñoadolescenteIntroduction: Hematological cancers are important causes of death in childhood and adolescence. Objective: To design the demographic and clinical profile of cases of hematological cancer reported for children and adolescents in a referral hospital in the city of São Luís, Maranhão, Brazil. Method: A retrospective observational study with secondary data collected from medical records of bone marrow tumor cases in patients aged up to 19 years registered in a public referral hospital for cancer treatment from 2005 to 2015. Patient’s profile was collected in addition to follow-up data. The chi-square and Fisher’s exact test were used in the statistical analysis. The significance level was 5% (p<0.05). Results: Cases of death were higher in patients diagnosed with non-Hodgkin’s lymphoma. Most patients with lymphoid leukemia were males aged up to 5 years, and the frequency of death in patients with lymphoid leukemia was lower in confirmed cases of type B lymphoblastic precursor cell leukemia when compared to the other categories. Conclusion: The findings suggest that most patients aged up to 19 years diagnosed with lymphoid leukemia were males and aged up to 5 years old.Introducción: Las neoplasias hematológicas son causas importantes de muerte en la niñez y la adolescencia. Objetivo: Caracterizar el perfil demográfico y clínico de los casos notificados de neoplasias hematológicas en niños y adolescentes en un hospital de referencia de la ciudad de São Luís, Maranhão, Brasil. Método: estudio observacional retrospectivo con datos secundarios recolectados de registros médicos de casos de tumores de médula ósea en pacientes de hasta 19 años registrados en un hospital público de referencia para tratamiento de cáncer de 2005 a 2015. Se recolectaron datos de caracterización. Datos generales de pacientes y seguimiento -up datos. En el análisis estadístico se utilizaron las pruebas de chi-cuadrado y exacta de Fisher. El nivel de significancia adoptado fue del 5% (p<0,05). Resultados: Los casos de muerte fueron mayores en pacientes con diagnóstico de linfoma no Hodgkin. La mayoría de los pacientes con leucemia linfoide eran varones de hasta 5 años, y la frecuencia de muerte en pacientes con leucemia linfoide fue menor en los casos confirmados de leucemia de células precursoras linfoblásticas tipo B en comparación con las otras categorías. Conclusión: Los hallazgos sugieren que la mayoría de los pacientes de hasta 19 años diagnosticados con leucemia linfoide eran hombres y tenían hasta 5 años.Introdução: As neoplasias hematológicas são importantes causas de morte na infância e adolescência. Objetivo: Caracterizar o perfil demográfico e clínico de casos notificados de neoplasias hematológicas em crianças e adolescentes em um hospital de referência do município de São Luís, Maranhão, Brasil. Método: Estudo observacional retrospectivo com dados coletados de prontuários médicos de casos de neoplasias hematológicas em pacientes com idade até 19 anos registrados em um hospital público de referência para tratamento oncológico, no período de 2005 a 2015. Foram coletados dados de caracterização geral dos pacientes e dados do seguimento do tratamento. Os testes qui-quadrado e exato de Fisher foram utilizados na análise estatística. O nível de significância adotado foi de 5% (p<0,05). Resultados: Os casos de óbito foram mais elevados nos pacientes diagnosticados com linfoma não Hodgkin. A maioria dos pacientes com leucemia linfoide era do sexo masculino com idade até 5 anos, e a frequência de óbito nos pacientes com leucemia linfoide foi mais baixa nos casos confirmados de leucemia linfoblástica de células precursoras tipo B em comparação a outras categorias. Conclusão: Os achados sugerem que a maioria dos pacientes com até 19 anos diagnosticados com leucemia linfoide era do sexo masculino e com idade até 5 anos.INCA2022-06-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfapplication/pdftext/htmlhttps://rbc.inca.gov.br/index.php/revista/article/view/235610.32635/2176-9745.RBC.2022v68n2.2356Revista Brasileira de Cancerologia; Vol. 68 No. 2 (2022): Apr./May/June; e-242356Revista Brasileira de Cancerologia; Vol. 68 Núm. 2 (2022): abr./mayo/jun.; e-242356Revista Brasileira de Cancerologia; v. 68 n. 2 (2022): abr./maio./jun.; e-2423562176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporenghttps://rbc.inca.gov.br/index.php/revista/article/view/2356/1735https://rbc.inca.gov.br/index.php/revista/article/view/2356/2350https://rbc.inca.gov.br/index.php/revista/article/view/2356/1789Copyright (c) 2022 Revista Brasileira de Cancerologiahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAraújo, Lucele Gonçalves Lima Rodrigues, Vandilson Pinheiro Silva, Melaine Mont’Alverne LawallAzevedo, Gabrielle Cristinne Alves Monteiro, Pablo de MatosFerreira, João Marcelo Saraiva Sousa, Huderson Macedo de 2022-10-27T16:47:54Zoai:rbc.inca.gov.br:article/2356Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2022-10-27T16:47:54Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
Perfil Demográfico y Clínico de Casos de Neoplasias Hematológicas en Niños y Adolescentes
Perfil Demográfico e Clínico de Casos de Neoplasias Hematológicas em Crianças e Adolescentes
title Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
spellingShingle Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
Araújo, Lucele Gonçalves Lima
neoplasias hematológicas
demografia
mortalidade
criança
adolescente
hematologic neoplasms
demography
mortality
child
adolescent
neoplasias hematológicas
demografía
mortalidad
niño
adolescente
title_short Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
title_full Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
title_fullStr Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
title_full_unstemmed Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
title_sort Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
author Araújo, Lucele Gonçalves Lima
author_facet Araújo, Lucele Gonçalves Lima
Rodrigues, Vandilson Pinheiro
Silva, Melaine Mont’Alverne Lawall
Azevedo, Gabrielle Cristinne Alves
Monteiro, Pablo de Matos
Ferreira, João Marcelo Saraiva
Sousa, Huderson Macedo de
author_role author
author2 Rodrigues, Vandilson Pinheiro
Silva, Melaine Mont’Alverne Lawall
Azevedo, Gabrielle Cristinne Alves
Monteiro, Pablo de Matos
Ferreira, João Marcelo Saraiva
Sousa, Huderson Macedo de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Araújo, Lucele Gonçalves Lima
Rodrigues, Vandilson Pinheiro
Silva, Melaine Mont’Alverne Lawall
Azevedo, Gabrielle Cristinne Alves
Monteiro, Pablo de Matos
Ferreira, João Marcelo Saraiva
Sousa, Huderson Macedo de
dc.subject.por.fl_str_mv neoplasias hematológicas
demografia
mortalidade
criança
adolescente
hematologic neoplasms
demography
mortality
child
adolescent
neoplasias hematológicas
demografía
mortalidad
niño
adolescente
topic neoplasias hematológicas
demografia
mortalidade
criança
adolescente
hematologic neoplasms
demography
mortality
child
adolescent
neoplasias hematológicas
demografía
mortalidad
niño
adolescente
description Introduction: Hematological cancers are important causes of death in childhood and adolescence. Objective: To design the demographic and clinical profile of cases of hematological cancer reported for children and adolescents in a referral hospital in the city of São Luís, Maranhão, Brazil. Method: A retrospective observational study with secondary data collected from medical records of bone marrow tumor cases in patients aged up to 19 years registered in a public referral hospital for cancer treatment from 2005 to 2015. Patient’s profile was collected in addition to follow-up data. The chi-square and Fisher’s exact test were used in the statistical analysis. The significance level was 5% (p<0.05). Results: Cases of death were higher in patients diagnosed with non-Hodgkin’s lymphoma. Most patients with lymphoid leukemia were males aged up to 5 years, and the frequency of death in patients with lymphoid leukemia was lower in confirmed cases of type B lymphoblastic precursor cell leukemia when compared to the other categories. Conclusion: The findings suggest that most patients aged up to 19 years diagnosed with lymphoid leukemia were males and aged up to 5 years old.
publishDate 2022
dc.date.none.fl_str_mv 2022-06-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2356
10.32635/2176-9745.RBC.2022v68n2.2356
url https://rbc.inca.gov.br/index.php/revista/article/view/2356
identifier_str_mv 10.32635/2176-9745.RBC.2022v68n2.2356
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2356/1735
https://rbc.inca.gov.br/index.php/revista/article/view/2356/2350
https://rbc.inca.gov.br/index.php/revista/article/view/2356/1789
dc.rights.driver.fl_str_mv Copyright (c) 2022 Revista Brasileira de Cancerologia
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Revista Brasileira de Cancerologia
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
text/html
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 68 No. 2 (2022): Apr./May/June; e-242356
Revista Brasileira de Cancerologia; Vol. 68 Núm. 2 (2022): abr./mayo/jun.; e-242356
Revista Brasileira de Cancerologia; v. 68 n. 2 (2022): abr./maio./jun.; e-242356
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
_version_ 1797042250146906112